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Chapuy, Nat. Med. 2017, n=277 Schmitz, NEJM 2018, n=415 Train Set, n=550 Test Set, n=149 Full Set, n=699 None Test Set, n=149 FN Sim 50%, random n=20 FP Sim 50%, random n=20 DLBCL Cell Lines, n=28 Schmitz, NEJM 2018, n=415

Set descriptions:

• Chapuy, Nat. Med. 2017, n=277 - Purity-filtered (20%) samples from Chapuy, Stewart, Dunford et al. Nat. Med. 2017
• Schmitz, NEJM 2018, n=415 - Purity-filtered (20%) samples from Schmitz et al. NEJM 2018
• Test Set, n=149 - All test set samples from the full combined set
• Train Set, n=550 - All train set samples from the full combined set
• FN Sim 50%, random n=20 - Random 20 samples from the False Negative (50%) simulation experiment
• FP Sim 50%, random n=20 - Random 20 samples from the False Positive (50%) simulation experiment
• DLBCL Cell Lines, n=28