Jaegil Kim

Lab Alumnus/Alumna

Lab Position: Computational Biologist

Google Scholar

Jaegil Kim

jaegil-kim-76907025

Selected Lab Papers

Genomic and transcriptomic analysis of checkpoint blockade response in advanced non-small cell lung cancer

Ravi A, Hellmann MD, Arniella MB, [...], Hacohen N, Getz G, Gainor JF
Nature Genetics (2023).
High-resolution profiling of lung adenocarcinoma identifies expression subtypes with specific biomarkers and clinically relevant vulnerabilities

Roh W, Geffen Y, Cha H, [...], Lee SH, Getz G
Cancer Research (2022).
Combined tumor and immune signals from genomes or transcriptomes predict outcomes of checkpoint inhibition in melanoma

Freeman SS, Sade-Feldman M, [...], Getz G, Hacohen N
Cell Reports Medcine 3 (2) (2022).
Analyses of non-coding somatic drivers in 2,658 cancer whole genomes

Rheinbay E, Nielsen MM, Abascal F, Wala JA, Shapira O, [...], Weischenfeldt J, Martincorena I, Pedersen JS, Getz G
Nature 578 (7793) 102-111 (2020).
The repertoire of mutational signatures in human cancer

Alexandrov LB, Kim J, Haradhvala NJ, Huang MN, [...], Getz G, Rozen SG, Stratton MR
Nature 578 (7793) 94-101 (2020).
Genomic analyses of PMBL reveal new drivers and mechanisms of sensitivity to PD-1 blockade

Chapuy B, Stewart C, Dunford AJ, [...], Getz G, Shipp MA
Blood 134 (26) 2369-2382 (2019).
Genomic analyses of flow-sorted Hodgkin Reed-Sternberg cells reveal complementary mechanisms of immune evasion

Wienand K, Chapuy B, Stewart C, Dunford AJ, Wu D, [...], Fromm JR, Getz G, Shipp MA
Blood Advances 3 (23) 4065-4080 (2019).
Scaling computational genomics to millions of individuals with GPUs

Taylor-Weiner A, Aguet F, [...], Getz G
Genome Biology 20 (1) (2019).
Passenger Hotspot Mutations in Cancer

Hess JM, [...], Lawrence MS, Getz G
Cancer Cell 36 (3) 288-301 (2019).
RNA sequence analysis reveals macroscopic somatic clonal expansion across normal tissues

Yizhak K, [...], Getz G
Science 364 (6444) (2019).
The Cancer Genome Atlas Expression Subtypes Stratify Response to Checkpoint Inhibition in Advanced Urothelial Cancer and Identify a Subset of Patients with High Survival Probability

Kim J, [...], Lerner SP
European Urology 75 (6) 961-964 (2019).
Comprehensive analysis of tumour initiation, spatial and temporal progression under multiple lines of treatment

Leshchiner I, Livitz D, Gainor J, Rosebrock D, [...], Shaw A, Getz G
bioRxiv (2019).
Tumor mutational landscape is a record of the pre-malignant state

Kübler K, Karlić R, [...], Foulkes WD, Polak P, Getz G
bioRxiv (2019).
Widespread Chromosomal Losses and Mitochondrial DNA Alterations as Genetic Drivers in Hürthle Cell Carcinoma

Gopal RK, Kübler K, [...], Getz G, McFadden DG
Cancer Cell 34 (2) 242-255.e5 (2018).
Distinct mutational signatures characterize concurrent loss of polymerase proofreading and mismatch repair

Haradhvala NJ, Kim J, Maruvka YE, [...], Mouw KW, Lawrence MS, Getz G
Nature Communications 9 (1) 1746 (2018).
Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes

Chapuy B, Stewart C, Dunford AJ, [...], Getz G, Shipp MA
Nature Medicine 24 (5) 679-690 (2018).
Scalable whole-exome sequencing of cell-free DNA reveals high concordance with metastatic tumors

Adalsteinsson VA, Ha G, Freeman SS, [...], Getz G, Love JC, Meyerson M
Nature Communications 8 (1) 1324 (2017).
Comprehensive molecular characterization of muscle invasive bladder cancer

Robertson AG, Kim J, [...], Weinstein JN, Kwiatkowski DJ, Lerner SP
Cell 171 (3) 540-556 (2017).
A mutational signature reveals alterations underlying deficient homologous recombination repair in breast cancer

Polak P, Kim J, Braunstein LZ, [...], Foulkes WD, Getz G
Nature Genetics 49 (10) 1476-1486 (2017).
Recurrent and functional regulatory mutations in breast cancer

Rheinbay E, Parasuraman P, [...], Getz G
Nature 547 (7661) 55-60 (2017).
Somatic ERCC2 mutations are associated with a distinct genomic signature in urothelial tumors

Kim J, Mouw KW, Polak P, [...], Getz G
Nature Genetics 48 (6) 600-606 (2016).
Mutational Strand Asymmetries in Cancer Genomes Reveal Mechanisms of DNA Damage and Repair

Haradhvala NJ, Polak P, [...], Lawrence MS, Getz G
Cell 164 (3) 538-549 (2016).
Whole-genome sequencing reveals activation-induced cytidine deaminase signatures during indolent chronic lymphocytic leukaemia evolution

Kasar S, Kim J, [...], Getz G, Brown JR
Nature Communications 6 (2015).
Integrative and comparative genomic analysis of lung squamous cell carcinomas in East Asian patients

Kim Y, Hammerman PS, Kim J, [...], Getz G, Meyerson M, Park K
Journal Clinical Oncology 32 (2) 121-8 (2014).
KDM4A lysine demethylase induces site-specific copy gain and rereplication of regions amplified in tumors

Black JC, Manning AL, Van Rechem C, Kim J, [...], Getz G, Whetstine JR
Cell 154 (3) 541-55 (2013).
Mutational heterogeneity in cancer and the search for new cancer-associated genes

Lawrence MS, Stojanov P, Polak P, [...], Lander ES, Getz G
Nature 499 (7457) 214-218 (2013).